ItWasMe covered the weather portion of where I live
Best: I'm right on the bus line (bus system goes all over town), right on a street with a bike lane, two blocks from a hippie food co-op with awesome coffee, and ten minutes on foot from campus. And I swear we have more ethnic restaurants--more restaurants period--than any other town of this size that I've seen; that is definitely one of the upshots of living in a college town.
Worst: There's little regulation on rental housing here; some of the neighborhoods look downright seedy.